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Cd244 Antibody / Natural killer cell receptor 2B4

CD244 antibody Dysregulated CD244 signaling is linked to impaired NK function in chronic viral infection, T cell exhaustion in tumors, and altered myeloid responses. Expression level, phosphorylation status, and adaptor association serve as readouts for immune competence in immuno-oncology, vaccine studies, and autoimmunity research, making precise detection with the CD244 antibody valuable for mechanistic and translational investigations. The CD244 antibody supports applications such as flow cytometry, immunohistochemistry, and western blot to quantify receptor abundance, track subcellular localization, and assess pathway modulation under genetic or pharmacologic perturbation. With high specificity and reproducible performance across primary cells and model systems, the CD244 antibody enables rigorous analysis of NK and T cell biology.

Product Specifications

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q07763

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant mouse protein (amino acids Q20-N374) was used as the immunogen for the Cd244 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, Direct ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Cd244 antibody is available for research use only.

Storage Conditions

After reconstitution, the Cd244 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Cd244 antibody should be determined by the researcher.

Location

Cell membrane

Image Legend

IHC staining of FFPE mouse spleen tissue with Cd244 antibody, HRP-secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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