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TAR DNA binding protein 43 Antibody / TDP43 / TARDBP

It participates in stress-responsive RNA granule dynamics and controlled phase behavior, linking RNA sorting to protein quality control pathways. Its nuclear enrichment, regulated export, and post-translational modification states offer quantitative readouts for studies of RNA processing, trafficking, and cellular adaptation in defined model systems. The TAR DNA binding protein 43 antibody from NSJ Bioreagents enables specific detection of endogenous TDP-43 in applications such as western blot, immunofluorescence, immunohistochemistry, immunoprecipitation, and RNA-protein pulldown workflows. Researchers use the TAR DNA binding protein 43 antibody to measure total protein levels, assess nuclear-cytoplasmic distribution, and evaluate biochemical fractionation or stress-induced relocalization when paired with appropriate complementary reagents. With high specificity and reproducible performance, the TAR DNA binding protein 43 antibody supports rigorous analysis of RNA-binding protein networks and post-transcriptional regulation. TAR DNA binding protein 43 antibody

Product Specifications

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:50-1:200, Immunofluorescence: 1:50-1:200

UniProt

Q13148

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide sequence specific to TAR DNA binding protein 43 was used as the immunogen for the TAR DNA binding protein 43 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG

Clone

26T75

Applications

WB, IF, IHC-P

Purity

Affinity chromatography

Format

Purified

Limitations

This TAR DNA binding protein 43 antibody is available for research use only.

Storage Conditions

After reconstitution, the TAR DNA binding protein 43 Antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the TAR DNA binding protein 43 antibody should be determined by the researcher.

Location

Nuclear, cytoplasmic

Image Legend

IHC staining of FFPE human glioma tissue with TAR DNA binding protein 43 antibody, HRP-secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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