POLG Antibody / DNA polymerase subunit gamma 1
Mutations in POLG are associated with a range of mitochondrial disorders, including progressive external ophthalmoplegia, Alpers-Huttenlocher syndrome, and ataxia-neuropathy syndromes. Studying POLG function helps researchers understand mitochondrial genome maintenance and the molecular basis of mitochondrial diseases. Using a high-quality POLG antibody allows for sensitive detection of the protein in assays such as western blot, immunohistochemistry, and immunofluorescence. A POLG antibody from NSJ Bioreagents offers consistent performance, supporting studies in mitochondrial biology, genetic disorders, and DNA repair mechanisms. Choosing the right POLG antibody is critical for producing reliable and reproducible research results.
Product Specifications
Specifications
Western blot: 1:500-1:2000
UniProt
P54098
Host
Rabbit
Reactivity
Human
Immunogen
A peptide sequence specific to DNA polymerase subunit gamma 1 was used as the immunogen for the POLG antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
24P93
Applications
WB
Purity
Affinity chromatography
Format
Purified
Limitations
This POLG antibody is available for research use only.
Storage Conditions
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the POLG antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) MCF7, 2) Jurkat and 3) SiHa cell lysate with POLG antibody. Predicted molecular weight ~140 kDa.
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items