SHP2 Antibody / PTPN11

SHP2 is essential for normal embryonic development, immune regulation, and tissue homeostasis. Mutations in SHP2 are associated with disorders such as Noonan syndrome, LEOPARD syndrome, and various cancers. Research on SHP2 provides valuable insights into the molecular mechanisms of signaling and their roles in both health and disease. Using a high-quality SHP2 antibody enables precise detection in applications including western blot, immunohistochemistry, and immunoprecipitation. An SHP2 antibody from NSJ Bioreagents offers consistent performance for studies on cell signaling, developmental biology, and oncogenesis. Selecting the right SHP2 antibody ensures accurate and reproducible research outcomes.

Product Specifications

Specifications

Western blot: 1:500, Immunohistochemistry (FFPE) : 1:50

UniProt

Q06124

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide sequence specific to SHP2 was used as the immunogen for the SHP2 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG

Clone

GBO-16

Applications

WB, IHC-P

Purity

Affinity chromatography

Format

Purified

Limitations

This SHP2 antibody is available for research use only.

Storage Conditions

After reconstitution, the SHP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the SHP2 antibody should be determined by the researcher.

Location

Nucleus, Cytoplasm

Image Legend

IHC staining of FFPE human lung cancer tissue with SHP2 antibody, HRP-secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.