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MYO7A Antibody / Unconventional Myosin-VIIa

Mutations in MYO7A are associated with hereditary hearing loss, Usher syndrome type 1B, and certain forms of retinitis pigmentosa. MYO7A is essential for maintaining stereocilia structure in cochlear hair cells and for transporting opsin-containing vesicles in retinal cells, highlighting its importance in sensory cell maintenance and signaling. Using a high-quality MYO7A antibody enables sensitive detection in applications such as western blot, immunohistochemistry, and immunofluorescence. An MYO7A antibody from NSJ Bioreagents provides consistent performance for research into sensory biology, genetic disorders, and intracellular transport mechanisms. Selecting the right MYO7A antibody is essential for achieving accurate and reproducible results.

Product Specifications

Specifications

Western blot: 1:500, Immunohistochemistry (FFPE) : 1:50

UniProt

Q13402

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide sequence specific to Unconventional Myosin-VIIa was used as the immunogen for the MYO7A antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG

Clone

AFCH-13

Applications

WB, IHC-P

Purity

Affinity chromatography

Format

Purified

Limitations

This MYO7A antibody is available for research use only.

Storage Conditions

After reconstitution, the MYO7A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Applications Notes

Optimal dilution of the MYO7A antibody should be determined by the researcher.

Location

Cytoplasm

Image Legend

IHC staining of FFPE human lung cancer tissue with MYO7A antibody, HRP-secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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