SMC4 Antibody / Structural maintenance of chromosomes protein 4

SMC4 is required for proper chromosome dynamics, DNA repair, and maintenance of genomic integrity. Dysregulation of SMC4 has been associated with chromosomal instability, cancer progression, and defective cell cycle control, highlighting its importance in both normal cellular division and disease research. Using a high-quality SMC4 antibody enables sensitive detection in applications such as western blot, immunohistochemistry, and immunoprecipitation. An SMC4 antibody from NSJ Bioreagents ensures reproducibility and reliability for studies involving chromosome structure, genome maintenance, and cancer biology. Selecting the right SMC4 antibody is essential for accurate and consistent results.

Product Specifications

Specifications

Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells

UniProt

Q9NTJ3

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human protein (amino acids K911-C1288) was used as the immunogen for the SMC4 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IF, FACS

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This SMC4 antibody is available for research use only.

Storage Conditions

After reconstitution, the SMC4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the SMC4 antibody should be determined by the researcher.

Location

Nuclear, cytoplasmic

Image Legend

Immunofluorescent staining of FFPE human HeLa cells with SMC4 antibody (green) and Alpha Tubulin mAb (red) . HIER: steam section in pH6 citrate buffer for 20 min.