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DEAD box protein 1 Antibody / DDX1

In addition to its role in RNA metabolism, DEAD box protein 1 has been implicated in maintaining genomic stability. It interacts with DNA repair proteins and contributes to the repair of double-strand breaks, suggesting it acts at the interface between RNA regulation and DNA integrity. By using a DEAD box protein 1 antibody, researchers can explore its functions in cellular stress responses, DNA repair pathways, and cell cycle progression. Elevated expression of DEAD box protein 1 has been observed in various cancers, linking it to tumor biology and uncontrolled cell proliferation. It has also been connected to viral replication, where it interacts with viral RNA to promote or regulate infection. These diverse roles make it a protein of interest in oncology, virology, and RNA biology. Employing a DEAD box protein 1 antibody provides valuable insights into its activity across multiple biological contexts. NSJ Bioreagents provides a high-quality DEAD box protein 1 antibody validated for applications including western blot, immunohistochemistry, and immunoprecipitation. Choosing a reliable DEAD box protein 1 antibody ensures accurate and reproducible detection in studies of RNA helicases, genomic stability, and disease mechanisms.

Product Specifications

Specifications

Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, Immunofluorescence: 5 µg/mL, Immunoprecipitation: 2ug per 500ug of lysate, ELISA: 0.1-0.5 µg/mL

UniProt

Q92499

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A human recombinant partial protein (amino acids K562-F740) was used as the immunogen for the DEAD box protein 1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, FACS, IF, IP, ELISA

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Limitations

This DEAD box protein 1 antibody is available for research use only.

Storage Conditions

After reconstitution, the DEAD box protein 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the DEAD box protein 1 antibody should be determined by the researcher.

Location

Nuclear, cytoplasmic

Image Legend

Immunofluorescent staining of FFPE human pancreas cancer tissue with DEAD box protein 1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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