Zebrafish Srsf1 Antibody / Serine/arginine-rich splicing factor 1 / Isoforms a & b

Predicted to enable mRNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be active in nuclear speck. Human ortholog (s) of this gene implicated in neurodevelopmental disorder with dysmorphic facies and behavioral abnormalities. Orthologous to human SRSF1 (serine and arginine rich splicing factor 1) .

Product Specifications

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

Q7SXP4, Q6NYA0

Host

Rabbit

Reactivity

Zebrafish

Immunogen

An E.coli-derived zebrafish recombinant protein (amino acids S2-E32) was used as the immunogen for the Zebrafish Srsf1 antibody. This antibody will detect the a and b isoforms.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Srsf1 antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Srsf1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Srsf1 antibody should be determined by the researcher.

Location

Nuclear, cytoplasmic

Image Legend

Immunohistochemical analysis of Srsf1a/b protein using Zebrafish Srsf1 antibody and paraffin-embedded zebrafish brain tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.