Zebrafish Bap1 Antibody / BRCA1-Associated Protein 1

BAP1, also known as BRCA1-associated protein-1, contains an acidic region, a highly charged C-terminal region, and 2 putative nuclear localization signals. BAP1 is a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression. BAP1 is expressed as a 4-kb mRNA in all human tissues, and mapped to 3p21.3.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

A1L2G3

Host

Rabbit

Reactivity

Zebrafish

Immunogen

An E.coli-derived zebrafish Bap1 recombinant protein (amino acids M1-D278) was used as the immunogen for the Zebrafish Bap1 antibody.

Clonality

Polyclonal

Isotype

Applications

IHC-P

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Bap1 antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Bap1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Bap1 antibody should be determined by the researcher.

Location

Nuclear, cytoplasmic

Image Legend

Immunohistochemical analysis of Bap1 protein using Zebrafish Bap1 antibody and paraffin-embedded zebrafish brain tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.