Zebrafish Bag5 Antibody

BAG family molecular chaperone regulator 5 is a protein that in humans is encoded by the BAG5 gene. The protein encoded by this gene is a member of the BAG1-related protein family. Bag5 is a negative regulator of both Hsp70 and parkin function that sensitizes dopaminergic neurons to injury-induced death and thus promotes neurodegeneration.

Product Specifications

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

F1QGM6

Host

Rabbit

Reactivity

Zebrafish

Immunogen

An E.coli-derived zebrafish Bag5 recombinant protein (amino acids K453-Y511) was used as the immunogen for the Zebrafish Bag5 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Bag5 antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Bag5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Bag5 antibody should be determined by the researcher.

Location

Cytoplasm, Nucleus

Image Legend

IHC staining of FFPE zebrafish heart tissue with Zebrafish Bag5 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.