Zebrafish Suz12 Antibody / Isoforms a & b

Predicted to enable chromatin DNA binding activity. Predicted to act upstream of or within chromatin organization. Predicted to be part of ESC/E (Z) complex and RSC-type complex. Predicted to be active in nucleus. Is expressed in gonad; midbrain hindbrain boundary; pharyngeal arch; and visual system. Human ortholog (s) of this gene implicated in renal Wilms' tumor. Orthologous to human SUZ12 (SUZ12 polycomb repressive complex 2 subunit) .

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 2-5 µg/mL, Western blot: 0.5-1 µg/mL

UniProt

Q6DC03, B0R1D5

Host

Rabbit

Reactivity

Zebrafish

Immunogen

An E.coli-derived zebrafish recombinant protein (amino acids K38-K448) was used as the immunogen for the Zebrafish Suz12 antibody. This antibody will detect the a and b isoforms.

Clonality

Polyclonal

Isotype

Applications

IHC-P, WB

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Suz12 antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Suz12 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Suz12 antibody should be determined by the researcher.

Location

Nuclear

Image Legend

Immunohistochemical analysis of Suz12a/b protein using Zebrafish Suz12 antibody and paraffin-embedded zebrafish brain tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.