Zebrafish Smarcb1 Antibody / Smarcb1a / Smarcb1b

Predicted to enable DNA binding activity and transcription coactivator activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to be located in nuclear chromosome. Predicted to be part of brahma complex; nBAF complex; and npBAF complex. Predicted to be active in nucleus. Human ortholog (s) of this gene implicated in Coffin-Siris syndrome 3; meningioma; rhabdoid cancer; rhabdoid tumor predisposition syndrome 1; and schwannomatosis (multiple) . Orthologous to human SMARCB1 (SWI/SNF related BAF chromatin remodeling complex subunit B1) .

Product Specifications

Specifications

Western blot: 0.5-1 µg/mL

UniProt

Q5U379, A0A2R8QP61

Host

Rabbit

Reactivity

Zebrafish

Immunogen

An E.coli-derived zebrafish SMARCB1a/b recombinant protein (amino acids E93-D346) was used as the immunogen for the Zebrafish Smarcb1 antibody. This antibody will detect the a and b isoforms.

Clonality

Polyclonal

Isotype

Applications

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Smarcb1 antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Smarcb1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Smarcb1 antibody should be determined by the researcher.

Image Legend

Western blot analysis of SMARCB1a/b protein using Zebrafish Smarcb1 antibody and zebrafish embryo tissue lysate. The predicted molecular weight of SMARCB1a/b is ~43 kDa.