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Zebrafish Gnrh2 Antibody / Gonadotropin-releasing hormone 2 / Progonadoliberin

Unlike Gnrh1, which is the main hypophysiotropic form regulating pituitary gonadotropin release, Gnrh2 is considered a non-hypophysiotropic GnRH variant and is thought to function in neuromodulation and reproductive behavior across vertebrates. In zebrafish, Gnrh2-expressing neurons have been implicated in the integration of sensory and hormonal signals, contributing to the fine-tuning of reproductive timing and behavior in response to environmental cues. Due to its evolutionary conservation and tissue-specific expression, zebrafish Gnrh2 is a valuable model for studying neuroendocrine regulation, sexual behavior, and the functional diversification of GnRH isoforms.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

Q5Y835

Host

Rabbit

Reactivity

Zebrafish

Immunogen

E. coli-derived zebrafish Gnrh2 recombinant protein (amino acids Q25-K86) was used as the immunogen for the Zebrafish Gnrh2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC-P

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Gnrh2 antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Gnrh2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Gnrh2 antibody should be determined by the researcher.

Image Legend

IHC staining of zebrafish Gnrh2 protein using Zebrafish Gnrh2 antibody, HRP-labeled secondary and DAB substrate. Gnrh2 was detected in a paraffin-embedded section of zebrafish eye tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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