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Zebrafish Lhcgr Antibody / Lutropin-choriogonadotropic hormone receptor

Zebrafish lhcgr is primarily expressed in the gonads, where it facilitates LH signaling necessary for reproductive maturation and fertility. Activation of Lhcgr triggers downstream signaling cascades, including cAMP/PKA pathways, leading to the production of sex steroids such as estradiol and testosterone. Functional studies in zebrafish have shown that Lhcgr is essential for proper follicular development and ovulation in females, and for Leydig cell function in males. As a conserved reproductive hormone receptor, zebrafish Lhcgr is a valuable model for investigating vertebrate reproductive endocrinology, hormone receptor signaling, and the genetic basis of fertility and gonadal disorders.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

Q6TCF8

Host

Rabbit

Reactivity

Zebrafish

Immunogen

E. coli-derived zebrafish Lhcgr recombinant protein (amino acids V51-V708) was used as the immunogen for the Zebrafish Lhcgr antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC-P

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Lhcgr antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Lhcgr antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Lhcgr antibody should be determined by the researcher.

Image Legend

IHC staining of zebrafish Lhcgr protein using Zebrafish Lhcgr antibody, HRP-labeled secondary and DAB substrate. Lhcgr was detected in a paraffin-embedded section of zebrafish kidney tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

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