Zebrafish Mmp13a Antibody / Interstitial collagenase

Mmp13a is particularly important during craniofacial morphogenesis, bone formation, and fin regeneration, where precise ECM remodeling is essential for cell migration, differentiation, and structural reorganization. Its expression is tightly regulated by signaling pathways such as Wnt, FGF, and TGF-Î², and it can be induced in response to injury or developmental cues. Due to its functional conservation with mammalian MMP13, zebrafish Mmp13a serves as a valuable model for studying osteogenesis, fibrosis, wound healing, and ECM-related diseases, including arthritis and cancer metastasis. Its robust expression during regeneration also makes it a useful biomarker for studies of tissue repair and regenerative biology.

Product Specifications

Specifications

Western Blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

F1QCX8

Host

Rabbit

Reactivity

Zebrafish

Immunogen

E. coli-derived zebrafish Mmp13a recombinant protein (amino acids D110-K476) was used as the immunogen for the Zebrafish Mmp13a antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Mmp13a antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Mmp13a antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Mmp13a antibody should be determined by the researcher.

Image Legend

IHC staining of FFPE zebrafish skin tissue with Zebrafish Mmp13a antibody, HRP-labeled secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.