Zebrafish Igf2a Antibody / Igf2 / Insulin-like growth factor 2

Igf2a functions by binding to the insulin-like growth factor 1 receptor (IGF1R), activating downstream signaling pathways such as PI3K-Akt and MAPK/ERK, which promote anabolic processes and inhibit apoptosis. In zebrafish, igf2a is expressed during early development and in growing tissues such as the heart, liver, and muscle, and has been shown to influence myogenesis, neurogenesis, and organ size regulation. Due to its importance in growth and regenerative pathways, zebrafish Igf2a is widely used as a model for studying developmental biology, metabolic regulation, and growth-related disorders. It is also of interest in research on wound healing, cardiac regeneration, and tumor biology.

Product Specifications

Specifications

Western Blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

Q9PUD0

Host

Rabbit

Reactivity

Zebrafish

Immunogen

E. coli-derived zebrafish Igf2a recombinant protein (amino acids G41-K197) was used as the immunogen for the Zebrafish Igf2a antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Igf2a antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Igf2a antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Igf2a antibody should be determined by the researcher.

Image Legend

IHC staining of zebrafish Igf2a protein using Zebrafish Igf2a antibody, HRP-labeled secondary and DAB substrate. Igf2a was detected in a paraffin-embedded section of zebrafish liver tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.