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Zebrafish Cxcl12 Antibody / Cxcl12a / Cxcl12b

Cxcl12 signals through its receptor Cxcr4, and this signaling axis is conserved across vertebrates. In zebrafish embryos, Cxcl12 is expressed in defined tissue regions and acts as a chemoattractant, guiding migrating cells to their correct destinations. It is also involved in vascular development, organ positioning, and fin regeneration. Because of its conserved function and well-characterized roles in developmental and immune processes, zebrafish Cxcl12 is widely used as a model for studying chemokine signaling, stem cell migration, tumor metastasis, and inflammatory responses. It is also a valuable tool in regenerative biology and drug discovery targeting chemokine pathways.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

Q8AV10

Host

Rabbit

Reactivity

Zebrafish

Immunogen

E. coli-derived zebrafish Cxcl12 recombinant protein (amino acids K24-V99) was used as the immunogen for the Zebrafish Cxcl12 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC-P

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Cxcl12 antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Cxcl12 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Cxcl12 antibody should be determined by the researcher.

Image Legend

IHC staining of zebrafish Cxcl12 protein using Zebrafish Cxcl12 antibody, HRP-labeled secondary and DAB substrate. Cxcl12 was detected in a paraffin-embedded section of zebrafish brain tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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