Zebrafish Fli1 Antibody / Friend leukemia integration 1 transcription factor
Friend leukemia integration 1 transcription factor (FLI1), also known as transcription factor ERGB, is a protein that in humans is encoded by the FLI1 gene, which is a proto-oncogene. It is mapped to 11q24.3. This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t (11;22) (q24; q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t (4;11) (q21; q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.
Product Specifications
Specifications
Western Blot: 0.5-1 µg/mL
UniProt
A0A8M9PLW9
Host
Rabbit
Reactivity
Zebrafish
Immunogen
E. coli-derived zebrafish Fli1 recombinant protein (amino acids M1-H426) was used as the immunogen for the Zebrafish Fli1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity chromatography
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This Zebrafish Fli1 antibody is available for research use only.
Storage Conditions
Product Datasheet
http://www.nsjbio.com/tds-pdf/zebrafish-fli1-antibody-friend-leukemia-integration-1-transcription-factor-rz1224
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Zebrafish Fli1 antibody should be determined by the researcher.
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