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Zebrafish Gfap Antibody / Glial fibrillary acidic protein

Gfap is strongly expressed in the neural tube, spinal cord, and brain ventricles of developing zebrafish embryos. These radial glial cells give rise to neurons and glia, making Gfap expression an important indicator of neurogenesis. In the mature zebrafish brain, Gfap remains expressed in astroglia and is associated with neural maintenance, repair, and regeneration. Because zebrafish have a high capacity for neural regeneration, Gfap is also commonly used to study injury responses and repair mechanisms in the brain and spinal cord. The conservation of Gfap structure and function across vertebrates makes zebrafish a valuable model for understanding the roles of glial cells in development, neurodegeneration, and central nervous system diseases. Zebrafish Gfap is widely applied in developmental neuroscience, regenerative medicine, and glial biology research. It is also a standard marker in transgenic models used to trace glial lineages and study brain architecture.

Product Specifications

Specifications

Western Blot: 0.5-1 µg/mL

UniProt

Q58EE9

Host

Rabbit

Reactivity

Zebrafish

Immunogen

E. coli-derived zebrafish Gfap recombinant protein (amino acids R123-P444) was used as the immunogen for the Zebrafish Gfap antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Gfap antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Gfap antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Gfap antibody should be determined by the researcher.

Image Legend

Western blot analysis of Gfap protein using Zebrafish Gfap antibody and 1) zebrafish head tissue lysates and 2) zebrafish embryo tissue lysates. Predicted molecular weight ~51 kDa.

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