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Zebrafish Insulin like growth factor 1 Antibody / Igf1

IGF1 is produced mainly in the liver and acts both locally and systemically through endocrine and paracrine signaling. It mediates many of the growth promoting effects of growth hormone and functions by binding to its specific receptor on the cell surface, triggering downstream signaling pathways that influence cell cycle progression, protein synthesis, and apoptosis inhibition. In zebrafish, insulin like growth factor 1 is involved in the development of multiple organs including the brain, heart, and skeletal muscle. It also supports fin regeneration and contributes to recovery from injury by promoting cell proliferation and tissue remodeling. IGF1 expression is sensitive to nutritional status and environmental factors, making it a key biomarker for growth and metabolic studies. Due to its strong conservation across vertebrates and its broad physiological importance, zebrafish insulin like growth factor 1 is widely used in research related to developmental biology, growth regulation, endocrine function, metabolic disease, and regenerative medicine.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

Q90VV9

Host

Rabbit

Reactivity

Zebrafish

Immunogen

E. coli-derived zebrafish Insulin like growth factor 1 recombinant protein (amino acids G45-M161) was used as the immunogen for the Zebrafish Insulin like growth factor 1 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC-P

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Insulin like growth factor 1 antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Insulin like growth factor 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Insulin like growth factor 1 antibody should be determined by the researcher.

Image Legend

IHC staining of zebrafish Insulin like growth factor 1 protein using Zebrafish Insulin like growth factor 1 antibody, HRP-labeled secondary and DAB substrate. Insulin like growth factor 1 was detected in a paraffin-embedded section of zebrafish pancreas tissue. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
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