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Zebrafish Rbm22 Antibody / RNA-binding protein 22

Zebrafish Rbm22 is an ortholog of the human RBM22 protein and exhibits a high degree of sequence and functional conservation. In both zebrafish and humans, Rbm22 is involved in regulating alternative splicing events that contribute to the diversity of the transcriptome and the regulation of gene expression. Its function is particularly important during early development when precise control of splicing is required for cell differentiation and tissue formation. There is currently limited evidence for multiple isoforms of zebrafish Rbm22, although alternative splicing is a common feature of RNA binding proteins, and further studies may reveal additional isoforms in the future. The zebrafish model provides an excellent system to study the conserved roles of Rbm22 in RNA metabolism and developmental processes. Antibodies targeting zebrafish Rbm22 protein are valuable for research in RNA biology, splicing regulation, and gene expression studies. Given its orthology to human RBM22, studies using zebrafish Rbm22 can provide insights into conserved mechanisms of splicing regulation and its potential links to human disease.

Product Specifications

Specifications

Western Blot: 0.5-1 µg/mL

UniProt

Q6NZZ9

Host

Rabbit

Reactivity

Zebrafish

Immunogen

E. coli-derived zebrafish Rbm22 recombinant protein (amino acids D17-R296) was used as the immunogen for the Zebrafish Rbm22 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB

Purity

Antigen affinity chromatography

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Limitations

This Zebrafish Rbm22 antibody is available for research use only.

Storage Conditions

After reconstitution, the Zebrafish Rbm22 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the Zebrafish Rbm22 antibody should be determined by the researcher.

Image Legend

Western blot analysis of Rbm22 protein using Zebrafish Rbm22 antibody and 1) zebrafish head, 2) whole female zebrafish, 3) whole male zebrafish and 4) zebrafish embryo tissue lysate. Predicted molecular weight ~47 kDa.

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