Psmc3 Antibody / Proteasome 26S subunit ATPase 3 / Tbp-1

Zebrafish Psmc3 is an ortholog of the human PSMC3 protein, sharing high sequence similarity and functional conservation. In both zebrafish and humans, Psmc3 contributes to the ATP dependent steps required for proteasome assembly and substrate processing. This evolutionary conservation makes zebrafish a suitable model for studying the roles of Psmc3 in development, stress responses, and diseases linked to impaired proteasome function, such as neurodegeneration and cancer. The use of a Zebrafish Psmc3 antibody allows researchers to detect and study the expression of Psmc3 in various tissues and developmental stages. These antibodies are valuable tools for applications including western blot, immunohistochemistry, and immunofluorescence, helping to clarify how proteasome activity is regulated in zebrafish. A Zebrafish Psmc3 antibody is also useful for comparative studies on proteasome regulation between zebrafish and mammalian systems. At this time there are no known isoforms of zebrafish Psmc3. By using a Zebrafish Psmc3 antibody, researchers can investigate its contribution to protein quality control and understand its functional relevance to human health and disease.