LI-Cadherin Antibody / Cadherin 17

Cadherin 17 (also known as LI Cadherin) is part of a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. LI-Cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 1-2 µg/mL

UniProt

Q12864

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 200-500 from human Cadherin 17 protein was used as the immunogen for the Cadherin-17 antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

CDH17/2614

Applications

IHC-P, WB

Purity

Protein G affinity

Format

Purified

Limitations

This Cadherin-17 antibody is available for research use only.

Storage Conditions

Aliquot the Cadherin-17 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the Cadherin-17 antibody should be determined by the researcher.

Location

Cell membrane

Image Legend

Western blot testing of human small intestine tissue lysate with LI-Cadherin antibody (clone CDH17/2614) . Predicted molecular weight ~92 kDa but may be observed at higher molecular weights due to glycosylation.