Recombinant MSLN Antibody / Mesothelin
Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 1-2 µg/mL
UniProt
Q13421
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 250-450 from human Mesothelin protein was used as the immunogen for the recombinant MSLN antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
MSLN/8331R
Applications
IHC-P, WB
Purity
Protein A affinity
Format
Purified
Limitations
This recombinant MSLN antibody is available for research use only.
Storage Conditions
Aliquot the recombinant MSLN antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant MSLN antibody should be determined by the researcher.
Location
Cell surface, Secreted
Image Legend
Frequently Asked Questions
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