Recombinant CDKN1B Antibody / p27Kip1

This MAb recognizes a 27kDa protein called p27Kip1/CDKN1B/Cyclin-dependent kinase inhibitor 1B, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb is excellent for staining of formalin-fixed tissues.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL

UniProt

P46527

Host

Mouse

Reactivity

Human

Immunogen

A recombinant human CDKN1B protein was used as the immunogen for the recombinant CDKN1B antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG2a κ

Clone

RCDKN1B/13245

Applications

IHC-P, WB

Purity

Protein G affinity

Format

Purified

Limitations

This recombinant CDKN1B antibody is available for research use only.

Storage Conditions

Aliquot the recombinant CDKN1B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the recombinant CDKN1B antibody should be determined by the researcher.

Location

Cytoplasm, Endosome, Nucleus

Image Legend

Western blot testing of human SK-BR-3 cell lysate with recombinant CDKN1B antibody (clone rCDKN1B/13245) . Commonly observed at ~27 kDa.

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