DLL3 Antibody / Delta-like protein 3

This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q9NYJ7

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 400-618 from human DLL3 protein was used as the immunogen for the DLL3 antibody.

Clonality

Monoclonal

Isotype

IgG2c κ

Clone

DLL3/9361

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Limitations

This DLL3 antibody is available for research use only.

Storage Conditions

Aliquot the DLL3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the DLL3 antibody should be determined by the researcher.

Location

Cell surface, Membrane

Image Legend

IHC staining of FFPE human brain tissue with DLL3 antibody (clone DLL3/9361) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.