HBEGF Antibody / Heparin-binding EGF-like growth factor / DT-R

Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL

UniProt

Q99075

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 1-208 from human Heparin-binding EGF-like growth factor protein was used as the immunogen for the HBEGF antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

HBEGF/9503

Applications

IHC-P, WB

Purity

Protein G affinity

Format

Purified

Limitations

This HBEGF antibody is available for research use only.

Storage Conditions

Aliquot the HBEGF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the HBEGF antibody should be determined by the researcher.

Location

Cell membrane, Membrane, Secreted

Image Legend

Western blot testing of mouse RAW264.7 cell lysate with HBEGF antibody. Predicted molecular weight ~23 kDa but may be observed at higher molecular weights due to glycosylation.