Recombinant HER2 Antibody / ErbB2 / Extracellular region
Recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P04626
Host
Rabbit
Reactivity
Human
Immunogen
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
ERBB2/13055R
Applications
IHC-P
Format
Purified
Limitations
This recombinant HER-2 antibody is available for research use only.
Storage Conditions
Aliquot the recombinant HER-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the recombinant HER-2 antibody should be determined by the researcher.
Location
Cell membrane
Image Legend
Frequently Asked Questions
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