PLA2R1 Antibody / Phospholipase A2 receptor 1

This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q13018

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 300-600 from human PLA2R1 protein was used as the immunogen for the PLA2R1 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

PLA2R1/4891

Applications

IHC-P

Purity

Protein G affinity

Format

Purified

Limitations

This PLA2R1 antibody is available for research use only.

Storage Conditions

Aliquot the PLA2R1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the PLA2R1 antibody should be determined by the researcher.

Location

Cell membrane, Secreted

Image Legend

IHC staining of FFPE human kidney tissue with PLA2R1 antibody (clone PLA2R1/4891) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.