PLA2R1 Antibody / Phospholipase A2 receptor 1

Receptor for secretory phospholipase A2 (sPLA2) . Acts as a receptor for phospholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. [UniProt]

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q13018

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 300-600 from human PLA2R1 protein was used as the immunogen for the PLA2R1 antibody.

Clonality

Monoclonal

Isotype

IgG2 κ

Clone

PLA2R1/4893

Applications

IHC-P

Purity

Protein A affinity

Format

Purified

Limitations

This PLA2R1 antibody is available for research use only.

Storage Conditions

Aliquot the PLA2R1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the PLA2R1 antibody should be determined by the researcher.

Location

Cell membrane, Secreted

Image Legend

IHC staining of FFPE human kidney tissue with PLA2R1 antibody (clone PLA2R1/4893) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.