PHPT1 Antibody / Phosphohistidine phosphatase 1
PHPT1 (phosphohistidine phosphatase 1), also known as 14 kDa phosphohistidine phosphatase, is a 125 amino acid enzyme belonging to the Janus protein family. Existing as a monomer in the cytoplasm, PHPT1 is an EDTAinsensitive phosphohistidine phosphatase. First identified in human adrenal gland, PHPT1 is highly expressed in skeletal muscle and heart, with lower expression in liver, pancreas and kidney. Overexpression of PHPT1 leads to specific phosphohistidine phosphatase activity towards phosphopeptide I, with no activity detected towards phosphotyrosine, phosphothreonine and phosphoserine peptides. PHPT1 is highly conserved among species, suggesting that it serves an essential functional role.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q9NRX4
Host
Mouse
Reactivity
Human
Immunogen
A recombinant human 14 kDa phosphohistidine phosphatase protein was used as the immunogen for the PHPT1 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
PHPT1/12053
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Limitations
This PHPT1 antibody is available for research use only.
Storage Conditions
Aliquot the PHPT1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.nsjbio.com/tds-pdf/phpt1-antibody-phosphohistidine-phosphatase-1-phpt112053-v5721
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the PHPT1 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
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