HK1 Antibody / Hexokinase 1
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL
UniProt
P19367
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 1-200 from human Hexokinase 1 protein was used as the immunogen for the HK1 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
HK1/9506
Applications
IHC-P, WB
Purity
Protein G affinity
Format
Purified
Limitations
This HK1 antibody is available for research use only.
Storage Conditions
Aliquot the HK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the HK1 antibody should be determined by the researcher.
Image Legend
Western blot testing of human brain tissue lysate with HK1 antibody (clone HK1/9506) . Predicted molecular weight ~120 kDa.
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