HSD17B13 Antibody / 7-beta hydroxysteroid dehydrogenase 13
Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is an enzyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q7Z5P4
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 1-200 of the human protein was used as the immunogen for the HSD17B13 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
HSD17B13/13102
Applications
IHC-P
Purity
Protein G affinity
Format
Purified
Limitations
This HSD17B13 antibody is available for research use only.
Storage Conditions
Aliquot the HSD17B13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the HSD17B13 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Frequently Asked Questions
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