17-beta-HSD 13 Antibody / HSD17B13
Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13, 17-beta-HSD 13) is an enzyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q7Z5P4
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 1-200 of the human protein was used as the immunogen for the 17-beta-HSD 13 antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
HSD17B13/13104
Applications
IHC-P
Purity
Protein G affinity
Format
Purified
Limitations
This 17-beta-HSD 13 antibody is available for research use only.
Storage Conditions
Aliquot the 17-beta-HSD 13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the 17-beta-HSD 13 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Frequently Asked Questions
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