Inhibin alpha chain Antibody

It recognizes a 47kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH) . Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same alpha subunit, covalently linked to 1 of 2 distinct subunits, beta-alpha or beta-beta. Inhibin belongs to the transforming growth factor beta (TFGb) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma.

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P05111

Host

Mouse

Reactivity

Human

Immunogen

A recombinant partial protein from human Inhibin alpha protein (within amino acids 233-362) was used as the immunogen for the Inhibin alpha chain antibody.

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

INHA/9354

Applications

IHC-P

Purity

Protein G affinity

Format

Purified

Limitations

This Inhibin alpha chain antibody is available for research use only.

Storage Conditions

Aliquot the Inhibin alpha chain antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the Inhibin alpha chain antibody should be determined by the researcher.

Location

Cytoplasm

Image Legend

IHC staining of FFPE human testis tissue with Inhibin alpha chain antibody (clone INHA/9354) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.