Recombinant BCL2L4 Antibody / BAX
Recognizes a protein of 21 kDa, identified as the Bax protein (also called Bcl-2-like protein 4 or BCL2L4) . This MAb is highly specific to BCL2L4 and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. BCL2L4 has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of BCL2L4 accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and BCL2L4 also counters the death repressor activity of Bcl-2.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL
UniProt
Q07812
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1-100 from human BAX protein was used as the immunogen for the recombinant BCL2L4 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
BAX/9925R
Applications
IHC-P, WB
Format
Purified
Limitations
This recombinant BCL2L4 antibody is available for research use only.
Storage Conditions
Aliquot the recombinant BCL2L4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant BCL2L4 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Frequently Asked Questions
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