S100A4 Antibody / S100 calcium-binding protein A4
S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100 genes include at least 25 members, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z. S100A4 exerts its function via direct interaction with a number of proteins including P53, P63, non-muscle myosin IIA, α6β4 integrin, and liprin b1. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL
UniProt
P26447
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 1-101 from human S100A4 protein was used as the immunogen for the S100A4 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
S100A4/6801
Applications
IHC-P, WB
Purity
Protein G affinity
Format
Purified
Limitations
This S100A4 antibody is available for research use only.
Storage Conditions
Aliquot the S100A4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the S100A4 antibody should be determined by the researcher.
Location
Cytoplasm, Nucleus
Image Legend
Frequently Asked Questions
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