ADP-ribosyl cyclase 1 Antibody / ADPRC1 / CD38

CD38/ADP-ribosyl cyclase 1 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34+ cells. The CD34+CD38- population of hematopoietic stems cells define the most pluripotent cells (e.g. blast colony forming cells) .

Product Specifications

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL

UniProt

P28907

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 1-200 from human CD38 protein was used as the immunogen for the ADP-ribosyl cyclase 1 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

CD38/9332

Applications

IHC-P, WB

Purity

Protein G affinity

Format

Purified

Limitations

This ADP-ribosyl cyclase 1 antibody is available for research use only.

Storage Conditions

Aliquot the ADP-ribosyl cyclase 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the ADP-ribosyl cyclase 1 antibody should be determined by the researcher.

Location

Membrane

Image Legend

IHC staining of FFPE human tonsil tissue with ADP-ribosyl cyclase 1 antibody (clone CD38/9332) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.