Cytomegalovirus Antibody / CMV-p65

Ten to forty percent of the patients with acquired immunodeficiency syndrome (AIDS) develop cytomegalovirus (CMV) infections. In some patients with AIDS, CMV is detected in the bronchoalveolar lavage fluid (BALF), urine, and other specimens, even when there are no symptoms of CMV disease. An indicator of active CMV infection is needed to facilitate the diagnosis of CMV disease in patients with AIDS or HIV infection. CMV p65 antigen was detected in the leukocytes of both the peripheral blood and BALF during the early phase of CMV disease.

Product Specifications

Specifications

ELISA, Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P06725

Host

Mouse

Reactivity

Cytomegalovirus

Immunogen

Recombinant CMV-p65 protein was used as the immunogen for the was used as the immunogen for the Cytomegalovirus antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG2b κ

Clone

RCMV/9827

Applications

ELISA, IHC-P

Purity

Protein G affinity

Format

Purified

Limitations

This Cytomegalovirus antibody is available for research use only.

Storage Conditions

Aliquot the Cytomegalovirus antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the Cytomegalovirus antibody should be determined by the researcher.

Location

Host cytoplasm, Host nucleus

Image Legend

IHC staining of FFPE human CMV-infected tissue with Cytomegalovirus antibody (clone rCMV/9827) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.