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Helicobacter pylori Antibody / H. Pylori

The spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcinoma and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. This antibody stains the individual H. pylori bacterium when it presents on the surface of the epithelium or in the cytoplasm of the epithelial cells in biopsy tissue sections from the antrum and body of the stomach.

Product Specifications

Specifications

ELISA, Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-3 µg/mL

Host

Mouse

Reactivity

Human

Immunogen

Total sonicate of Helicobacter pylori was used as the immunogen for the Helicobacter pylori antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

HP/1334

Applications

ELISA, FACS, IF

Purity

Protein G affinity

Format

Purified

Limitations

This Helicobacter pylori antibody is available for research use only.

Storage Conditions

Aliquot the Helicobacter pylori antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the Helicobacter pylori antibody should be determined by the researcher.

Image Legend

SDS-PAGE analysis of purified, BSA-free Helicobacter pylori antibody (clone HP/1334) as confirmation of integrity and purity.

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