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Human Kallikrein 4 / KLK-4 Protein, His Tag (active enzyme, HPLC verified)

Selected Variant

KL4-H52H3-1mg

Size: 1 mg

Kallikrein-related peptidase 4 (KLK4) is a secreted serine protease primarily expressed in teeth, prostate, and other tissues. It plays a key role in enamel maturation by degrading enamel matrix proteins. Dysregulation of KLK4 is linked to dental defects, cancer progression, and other pathologies, making it a biomarker and potential therapeutic target.

Product Specifications

Background

Kallikrein-related peptidase 4 (KLK4) is a secreted serine protease primarily expressed in teeth, prostate, and other tissues. It plays a key role in enamel maturation by degrading enamel matrix proteins. Dysregulation of KLK4 is linked to dental defects, cancer progression, and other pathologies, making it a biomarker and potential therapeutic target.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.3 kDa. The protein migrates as 29-30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Expression Region

Ser 27 - Ser 254

Target

Kallikrein 4

Conjugation

Unconjugated

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

50 mM Tris, 150 mM NaCl, pH7.5

Molecular Weight

26.3 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

250ug*4

Host or Source

HEK293

Species

Human

Protein ID

Q9Y5K2

Preservative

Trehalose

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