Human Kallikrein 4 / KLK-4 Protein, His Tag (active enzyme, HPLC verified)
Kallikrein-related peptidase 4 (KLK4) is a secreted serine protease primarily expressed in teeth, prostate, and other tissues. It plays a key role in enamel maturation by degrading enamel matrix proteins. Dysregulation of KLK4 is linked to dental defects, cancer progression, and other pathologies, making it a biomarker and potential therapeutic target.
Product Specifications
Background
Kallikrein-related peptidase 4 (KLK4) is a secreted serine protease primarily expressed in teeth, prostate, and other tissues. It plays a key role in enamel maturation by degrading enamel matrix proteins. Dysregulation of KLK4 is linked to dental defects, cancer progression, and other pathologies, making it a biomarker and potential therapeutic target.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.3 kDa. The protein migrates as 29-30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region
Ser 27 - Ser 254
Target
Kallikrein 4
Conjugation
Unconjugated
Tag
C-10xHis
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
50 mM Tris, 150 mM NaCl, pH7.5
Molecular Weight
26.3 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
250ug*4
Host or Source
HEK293
Species
Human
Protein ID
Q9Y5K2
Preservative
Trehalose
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