Biotinylated Human HLA-A*02:01&B2M&p53 (HMTEVVRRC) Complex Protein (Monomer, MALS verified)
TP53 has been recognized as a tumor suppressor. 50% of cancers carry a TP53 mutation while many others affect other pathway components. High-copy numbers of WT p53 peptide-MHC class I complexes were detected on tumor cells as compared to low copies on normal cells. The Human HLA-A*0201 p53 (HMTEVVRRC) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and HMTEVVRRC peptide of the p53.
Product Specifications
Background
Specifications
Expression Region
Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & HMTEVVRRC
Target
HLA-A*0201 & B2M & p53 (HMTEVVRRC)
Conjugation
Biotin-labeled
Tag
C-10xHis & C-Avi
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
Purity
95%
Format
Liquid
Buffer
PBS, pH7.4
Molecular Weight
36.3 kDa and 11.7 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
200ug*1
Host or Source
HEK293
Species
Human
Protein ID
AAA59606.1 (HLA-A*02:01) & P61769-1 (B2M) & HMTEVVRRC
Preservative
Trehalose
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