Biotinylated Human HLA-DPA1*01:03&HLA-DPB1*04:01&CLIP (PVSKMRMATPLLMQA) Complex Protein (Monomer, MALS verified)

HLA-DP is a isotype of MHC Class II responsible for presenting foreign antigens to the immune system's helper T-cells. The CLIP peptide, derived from the invariant chain, occupies the peptide-binding groove of the newly synthesized HLA-DP molecule to prevent it from loading irrelevant peptides inside the cell.

Biotinylated Human HLA-DPA1*01:03&HLA-DPB1*04:01&CLIP (PVSKMRMATPLLMQA) Complex Protein is produced by co-expression of HLA-DPA1*01:03 and HLA-DPB1*04:01 loaded with CLIP peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 29.5 kDa and 29.2 kDa. The protein migrates as 38-41 kDa and 33-36 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.