Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Biotinylated Human HLA-A*01:01&B2M&MAGEA3 (EVDPIGHLY) Complex Protein (Monomer, MALS verified)

The HLA-A*01:01 allele is a prevalent human MHC class I variant, and its peptide-binding specificity determines the immune response in individuals carrying this allele. MAGEA3 is a member of the Melanoma-Associated Antigen family, characterized by its restricted expression in normal tissues (primarily testes and placenta) but frequent re-expression in various tumors, such as melanoma, lung cancer, and others.

Product Specifications

Background

The HLA-A*01:01 allele is a prevalent human MHC class I variant, and its peptide-binding specificity determines the immune response in individuals carrying this allele. MAGEA3 is a member of the Melanoma-Associated Antigen family, characterized by its restricted expression in normal tissues (primarily testes and placenta) but frequent re-expression in various tumors, such as melanoma, lung cancer, and others.

Specifications

Biotinylated Human HLA-A*01:01&B2M&MAGEA3 (EVDPIGHLY) Complex Protein is produced by co-expression of HLA-A*01:01 and B2M loaded with MAGEA3 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 36.0 kDa and 13.8 kDa. The protein migrates as 40-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Expression Region

Gly 25-Thr 305 (HLA-A*01:01) & Ile 21 - Met 119 (B2M) & EVDPIGHLY

Target

HLA-A*0101 & B2M & MAGEA3 (EVDPIGHLY)

Conjugation

Biotin-labeled

Tag

C-10xHis & C-Avi

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

PBS, pH7.4

Molecular Weight

36.0 kDa and 13.8 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

200ug*1

Host or Source

HEK293

Species

Human

Protein ID

Q5SUL5 (HLA-A*01:01) & P61769-1 (B2M) & EVDPIGHLY

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

hsa-miR-6894-5p miRNA Inhibitor
MIH03746 2x 5.0 nmol

hsa-miR-6894-5p miRNA Inhibitor

Ask
View Details
LentimiRa-mmu-miR-7658-5p Vector
mm42034 500 ng

LentimiRa-mmu-miR-7658-5p Vector

Ask
View Details
UBE2L3, NT (Ubiquitin-conjugating Enzyme E2 L3, Ubiquitin-conjugating Enzyme E2-F1, Ubiquitin-protein Ligase L3, Ubiquitin Carrier Protein L3, L-UBC, UbcH7, UBCE7) (MaxLight 650) discontinued
U1000-88A-ML650 100 µL

UBE2L3, NT (Ubiquitin-conjugating Enzyme E2 L3, Ubiquitin-conjugating Enzyme E2-F1, Ubiquitin-protein Ligase L3, Ubiquitin Carrier Protein L3, L-UBC, UbcH7, UBCE7) (MaxLight 650) discontinued

Ask
View Details
SPATA2L, ID (SPATA2L, C16orf76, Spermatogenesis-associated protein 2-like protein) (APC) discontinued
042206-APC 200 µL

SPATA2L, ID (SPATA2L, C16orf76, Spermatogenesis-associated protein 2-like protein) (APC) discontinued

Ask
View Details
CD45 (FITC) discontinued
516382-01 20 Tests

CD45 (FITC) discontinued

Ask
View Details
CD45 (FITC) discontinued
516382-02 100 Tests

CD45 (FITC) discontinued

Ask
View Details