Human GPR75 Full Length Protein (VLP)
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
Product Specifications
Background
Specifications
This protein .
Expression Region
Asn 2 - Val 540
Target
GPR75
Conjugation
Unconjugated
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 12 months under sterile conditions.
Endotoxin
1.0 EU per μg
Format
Liquid
Buffer
PBS, Arginine, pH7.4
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
250ug*2
Host or Source
HEK293
Species
Human
Protein ID
O95800
Preservative
Trehalose
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