Human FGF-10 / KGF 2 Protein, His Tag, Research Grade
Fibroblast Growth Factor 10 (FGF 10) is an evolutionary conserved secreted growth factor mediating mostly mesenchymal to epithelial signaling. FGF 10 belongs to the FGF 7 subfamily and shares similar biochemical and amino acid sequences with its constituent members (FGF3, FGF 7 and FGF 22) . As a paracrine FGF, FGF 10 elicits its biological responses by activating the fibroblast growth factor receptor 2b (FGF R 2b), is crucial for governing proximal distal outgrowth as well as patterning and acts upstream of the known apical ectodermal ridge (AER) marker FGF 8. FGF10 is also implicated in pancreatic cancer, and that overexpression of FGFR2b is associated with metastatic invasion.
Product Specifications
Background
Specifications
Expression Region
Gln 38 - Ser 208
Target
FGF-10
Conjugation
Unconjugated
Tag
N-10xHis
Stability
Endotoxin
0.01 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, 0.2 M Arginine, pH7.4
Molecular Weight
21.3 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
50ug*1
Host or Source
E. coli
Species
Human
Protein ID
O15520-1
Preservative
Trehalose
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