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Influenza A virus (Sydney/1359/2024) HA (H3N2) Protein, His Tag (MALS verified)

Influenza A virus (Sydney/1359/2024) HA (H3N2) Protein, His Tag (HA2-V52Hb) is expressed from human 293 cells (HEK293) . It contains AA Lys 18 - Trp 530 (Accession # EPI_ISL_19711425, GISAID) .

Product Specifications

Background

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Hemagglutinin also plays a major role in the determination of host range restriction and virulence. As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 62.8 kDa . The protein migrates as 65-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Expression Region

Lys 18 - Trp 530

Target

Hemagglutinin/HA (Influenza Virus)

Conjugation

Unconjugated

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

0.1 M Sodium citrate, pH5.5

Molecular Weight

62.8 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

1mg*1

Host or Source

HEK293

Species

Influenza A virus (Sydney/1359/2024)

Protein ID

EPI_ISL_19711425

Preservative

Trehalose

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