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SARS-CoV-2 Spike RBD Protein, His Tag (NB.1.8.1) (MALS verified)

SARS‑CoV‑2 NB.1.8.1 is an Omicron‑descendant variant under monitoring, first detected in early 2025. It carries multiple spike mutations linked to immune escape and shows a growth advantage over co‑circulating BA.2.86/JN.1 lineages2. While currently at low prevalence in many regions, it is spreading in parts of Asia and is expected to rise, though no major increase in disease severity is anticipated.

Product Specifications

Background

SARS‑CoV‑2 NB.1.8.1 is an Omicron‑descendant variant under monitoring, first detected in early 2025. It carries multiple spike mutations linked to immune escape and shows a growth advantage over co‑circulating BA.2.86/JN.1 lineages2. While currently at low prevalence in many regions, it is spreading in parts of Asia and is expected to rise, though no major increase in disease severity is anticipated.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.7 kDa. The protein migrates as 35-41 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Expression Region

Arg 319 - Lys 537

Target

Spike RBD

Conjugation

Unconjugated

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

PBS, pH7.4

Molecular Weight

26.7 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

SARS-CoV-2

Protein ID

QHD43416.1 (I332V, G339H, K356T, S371F, S373P, S375F, T376A, R403K, D405N, R408S, K417N, A435S, N440K, V445H, G446S, N450D, L452W, L455S, F456L, N460K, S477N, T478I, N481K, E484K, F486P, Q493E, Q498R, N501Y, Y505H)

Preservative

Trehalose

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