SARS-CoV-2 Spike RBD Protein, His Tag (LF.7)

The SARS‑CoV‑2 lineage LF.7 is a subvariant within the JN.1 family, identified through genomic surveillance in 2024–2025. It carries multiple Spike protein mutations, some within the receptor‑binding domain, potentially affecting antibody recognition and viral fitness. LF.7 and its sublineages (e.g., LF.7.2.1) have been detected across several regions, showing moderate growth advantage over earlier strains. Preliminary studies suggest certain mutations may enhance immune evasion, though impacts on ACE2 binding vary. Continuous monitoring is recommended to assess its epidemiological significance, vaccine effectiveness, and role in ongoing SARS‑CoV‑2 evolution.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 35.1 kDa.

Expression Region

Arg 319 - Lys 537

Target

Spike RBD

Conjugation

Unconjugated

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Format

Powder

Molecular Weight

35.1 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Storage Conditions

-20°C

Package Size

1mg*1

Host or Source

HEK293

Species

SARS-CoV-2

Protein ID

QHD43416.1 (I332V, G339H, R346T, K356T, S371F, S373P, S375F, T376A, R403K, D405N, R408S, K417N, N440K, K444R, G446S, N450D, L452W, L455S, F456L, N460K, S477N, T478K, N481K, E484K, F486P, Q498R, N501Y, Y505H)